4-(2-Methyl-2-hydrooxypropylamino)-5,6-dihydrothieno-(2,3-B)thiopyran-2-sulfonamid-7,7-dioxid

4-(2-Methyl-2-hydroxypropylamino)-5,6-dihydrothieno[2,3-b]thiopyran-2- sulfon a mide-7,7-dioxide is a major mammalian metabolite of 4-(2-methylpropylamino)-5,6-dihydrothieno[2,3-b]thiopyran-2-sulfonamid e-7,7-diox ide and is itself an active carbonic anhydrase inhibitor useful in the treatment of oc...

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Main Authors ZACCHEI, ANTONY G., AMBLER, PA 19002, US, HOFFMAN, JACOB M., NORTH WALES, PA 19454, US, LEE, LING L., LANSDALE, PA 19446, US, VARGA, SANDOR L., HARLEYSVILLE, PA 19438, US
Format Patent
LanguageGerman
Published 08.06.1995
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:4-(2-Methyl-2-hydroxypropylamino)-5,6-dihydrothieno[2,3-b]thiopyran-2- sulfon a mide-7,7-dioxide is a major mammalian metabolite of 4-(2-methylpropylamino)-5,6-dihydrothieno[2,3-b]thiopyran-2-sulfonamid e-7,7-diox ide and is itself an active carbonic anhydrase inhibitor useful in the treatment of ocular hypertension by topical administration.
Bibliography:Application Number: DE19906015919T