Verfahren zur Herstellung von Castanosperminestern

1-Esters of castanospermine have been prepared enzymatically from appropriate activated esters using subtilisin. The esters obtained in this way can be further reacted enzymatically to give diesters which can, in turn, be selectively hydrolyzed to give monoesters in good yield.

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Bibliographic Details
Main Authors MARGOLIN, ALEXEY L., FISHERS, IN 46038, US, DELINCK, DEBORAH L., INDIANAPOLIS, IN 46268, US
Format Patent
LanguageGerman
Published 11.05.1995
Edition6
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HETEROCYCLIC COMPOUNDS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:1-Esters of castanospermine have been prepared enzymatically from appropriate activated esters using subtilisin. The esters obtained in this way can be further reacted enzymatically to give diesters which can, in turn, be selectively hydrolyzed to give monoesters in good yield.
Bibliography:Application Number: DE19906015499T