KUPPLUNGSMITTEL UND STERISCH GEHINDERTE, MIT DISULFID GEBUNDENE KONJUGATE DARAUS

This invention discloses heterobifunctional coupling agents for making a wide array of molecular conjugates. The agents contain a sterically hindered thiol, linked through a spacer arm to a second group reactive toward nucleophiles such as 1 DEG and 2 DEG amines or reactive thiols that are present o...

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Main Authors NITECKI, DANUTE, E., BERKELEY, CA 94709, US, MORELAND, MARGARET, BERKELEY, CA 94702, US, GREENFIELD, I., LAWRENCE, PLEASANT HILL, CA 94523, US
Format Patent
LanguageGerman
Published 25.04.1996
Edition6
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PHYSICS
TESTING
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Summary:This invention discloses heterobifunctional coupling agents for making a wide array of molecular conjugates. The agents contain a sterically hindered thiol, linked through a spacer arm to a second group reactive toward nucleophiles such as 1 DEG and 2 DEG amines or reactive thiols that are present on biological and organic materials. The coupling agents are useful for making conjugates containing a sterically hindered linkage.
Bibliography:Application Number: DE19896021982T