OSMOTISCHES VERABREICHUNGSSYSTEM

An osmotic pharmaceutical tablet is described which comprises a single-layer compressed core surrounded by a water permeable layer having a passageway. The single-layer core contains (i) a non-ripening drug having a solubility per dose less than about 1 mL-1, (ii) about 2.0% to about 20% by weight o...

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Main Authors FRIESEN, DWAYNE THOMAS, MACDONALD, BRUCE CLINTON, FERGIONE, MICHAEL BRUCE, MILLER, LEE ANTHONY, ROY, MICHAEL CHRISTOPHER, BILLOTE, ANNE MARTINE, CARRIER, REBECCA LYN, SHAMBLIN, SHERI LYNN, WATERMAN, KENNETH CRAIG
Format Patent
LanguageGerman
Published 11.10.2007
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:An osmotic pharmaceutical tablet is described which comprises a single-layer compressed core surrounded by a water permeable layer having a passageway. The single-layer core contains (i) a non-ripening drug having a solubility per dose less than about 1 mL-1, (ii) about 2.0% to about 20% by weight of a hydroxyethylcellulose having a weight-average, molecular weight from about 300,000 to about 2,000,000, and (iii) an osmagent.
Bibliography:Application Number: DE20036009832T