New oxo-prostaglandin sulphonamide analogues

New 9-(oxo or oximino)-prostaglandin sulphonamide analogues of formula (I), salts of (I; R = COOH) with bases and clathrates with alpha , beta or psi -cyclodextrin and (I) in liposome-encapsulated form are new: R = 2-oxazolin-2-yl, 5,5-dimethyl-1,3-dioxan-2-yl, 1H-tetrazol-5-yl, etc.; X = (CH2)p or...

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Bibliographic Details
Main Authors KLAR, ULRICH., 13503 BERLIN, DE, VORBRUEGGEN, HELMUT, DR., 13507 BERLIN, DE, REHWINKEL, HARTMUT., 12051 BERLIN, DE, THIERAUCH, KARL-HEINZ., 14169 BERLIN, DE, VERHALLEN, PETER., 13158 BERLIN, DE
Format Patent
LanguageEnglish
German
Published 22.06.1995
Edition6
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:New 9-(oxo or oximino)-prostaglandin sulphonamide analogues of formula (I), salts of (I; R = COOH) with bases and clathrates with alpha , beta or psi -cyclodextrin and (I) in liposome-encapsulated form are new: R = 2-oxazolin-2-yl, 5,5-dimethyl-1,3-dioxan-2-yl, 1H-tetrazol-5-yl, etc.; X = (CH2)p or CH2O; p = 0-5; L = O or NOR ; Z = direct bond, -CH=CH- or -C?=C-; R = opt. substd. 1-10C alkyl; R = OR or R ; m = 0-3; R = opt. substd. 1-10C alkyl; R = H, 1-10C alkyl, or 6-12C aryl or 7-16C aralkyl (both opt. substd.) or protecting gp.; R = H, 1-10C alkyl or 6-12C aryl or 7-16C aralkyl (both opt. substd.).
Bibliography:Application Number: DE19934343776