VERWENDUNG VOM "CARTILAGE-INDUCING FAKTOR B(CIF-B)" ZUR HERSTELLUNG EINES ARZNEIMITTELS GEGEN DAS WACHSTUM VON TUMOREN

A polypeptide called cartilage-inducing factor B (CIF-B) or transforming growth factor beta 2 (TGF- beta 2) that is found in bone and has heretofore been identified as having in vitro cartilage-inducing activity, TGF- beta activity, and anti-inflammatory activity has now been found to possess potent...

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Main Authors TODARO, GEORGE J., SEATTLE WASHINGTON 98112, US, RANCHALIS, JANE E., SEATTLE WAHINGTON 98119, US, TWARDZIK, DANIEL R., BAINBRIDGE WASHINGTON 98110, US, PIEZ, KARL A., MENLO PARK CALIFORNIA 94025, US, MCPHERSON, JOHN M., SUNNYVALE CALIFORNIA 94086, US
Format Patent
LanguageGerman
Published 17.12.1992
Edition5
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A polypeptide called cartilage-inducing factor B (CIF-B) or transforming growth factor beta 2 (TGF- beta 2) that is found in bone and has heretofore been identified as having in vitro cartilage-inducing activity, TGF- beta activity, and anti-inflammatory activity has now been found to possess potent oncostatic activity. CIF-B showed oncostatic activity on human and animal tumors, including carcinomas, adenocarcinomas, lymphomas, and melanomas.
Bibliography:Application Number: DE19873781250T