Proline derivatives
Proline derivatives of the formula I in which R and R can be identical or different and are H, alkyl with 1-4 C atoms or benzyl, R is alkyl with 1-6 C atoms, R is CH3 or -(CH2)4-NH2, R is CH3 or -(CH2)2-Ar, R and R are each H or together are a C-C bond and Ar is phenyl which is unsubstituted or subs...
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| Main Authors | , , , , |
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| Format | Patent |
| Language | English German |
| Published |
16.04.1987
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| Edition | 4 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Proline derivatives of the formula I in which R and R can be identical or different and are H, alkyl with 1-4 C atoms or benzyl, R is alkyl with 1-6 C atoms, R is CH3 or -(CH2)4-NH2, R is CH3 or -(CH2)2-Ar, R and R are each H or together are a C-C bond and Ar is phenyl which is unsubstituted or substituted one or more times by alkyl with 1-4 C atoms, alkoxy with 1-4 C atoms, Cl and/or CN, and their salts inhibit the effect of angiotensin converting enzyme and lower blood pressure. |
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| AbstractList | Proline derivatives of the formula I in which R and R can be identical or different and are H, alkyl with 1-4 C atoms or benzyl, R is alkyl with 1-6 C atoms, R is CH3 or -(CH2)4-NH2, R is CH3 or -(CH2)2-Ar, R and R are each H or together are a C-C bond and Ar is phenyl which is unsubstituted or substituted one or more times by alkyl with 1-4 C atoms, alkoxy with 1-4 C atoms, Cl and/or CN, and their salts inhibit the effect of angiotensin converting enzyme and lower blood pressure. |
| Author | OTTO,MINCK,KLAUS GANTE,JOACHIM,DR RADUNZ,HANS-ECKARD,DR SCHMITGES,CLAUS,DR WEBER,WOLF-DIETRICH,DR |
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| Discipline | Medicine Chemistry Sciences |
| DocumentTitleAlternate | PROLINDERIVATE |
| Edition | 4 |
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| Notes | Application Number: DE19853536446 |
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| PublicationDate | 19870416 |
| PublicationDateYYYYMMDD | 1987-04-16 |
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| PublicationYear | 1987 |
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| Snippet | Proline derivatives of the formula I in which R and R can be identical or different and are H, alkyl with 1-4 C atoms or benzyl, R is alkyl with 1-6 C atoms, R... |
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| SubjectTerms | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| Title | Proline derivatives |
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