PLATIN-DIAMIN-KOMPLEX
This invention relates to a novel platinum-diamine complexes represented by the general formula: wherein R1 and R2 each represents a lower alkyl group having 1 to 3 carbon atoms or jointly represent an alkylene group having 3 to 6 carbon atoms; two X's each represents a halogen atom, or jointly...
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Main Authors | , , |
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Format | Patent |
Language | German |
Published |
02.05.1985
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Edition | 3 |
Subjects | |
Online Access | Get full text |
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Summary: | This invention relates to a novel platinum-diamine complexes represented by the general formula: wherein R1 and R2 each represents a lower alkyl group having 1 to 3 carbon atoms or jointly represent an alkylene group having 3 to 6 carbon atoms; two X's each represents a halogen atom, or jointly represent a group represented by in which R3 is a lower alkyl group or a group represented by -OM (wherein M is an atom which can become a monovalent cation); Y is -OH or a halogen atom; and n is 0 or 1, and n is 1 when R1 and R2 jointly represent an alkylene group having 5 carbon atoms and X is chlorine. The platinum-diamine complex of this invention has an excellent antitumor activity and a lower renal toxicity than cis-Platin now widely used as a carcinostatic as clinical medicine, and is expected as a carcinostatic lowered in toxicity. |
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Bibliography: | Application Number: DE19843438440 |