NEUE BENZIMIDAZOLE, IHRE HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL

Benzimidazoles of the formula in which R1 denotes a hydroxyl, alkoxy, phenylalkoxy, cyanoalkoxy, alkylsulphenyl, alkylsulphinyl, alkylsulphonyl, aminosulphonyl, alkylaminosulphonyl, dialkylaminosulphonyl, alkylsulphoximino, alkenyloxy or alkynyloxy group, R2 denotes a hydrogen atom, a hydroxyl, alko...

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Main Authors MEEL, JAKOBUS C.A. VAN., 7950 BIBERACH, DE, AUSTEL, VOLKHARD. DR., 7950 BIBERACH, DE, DIEDEREN, WILLI, REIFFEN, MANFRED. DR, HAUEL, NORBERT. DR, MUELLER, ERICH. DR, HEIDER, JOACHIM. DR., 7951 WARTHAUSEN, DE
Format Patent
LanguageGerman
Published 04.07.1985
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Benzimidazoles of the formula in which R1 denotes a hydroxyl, alkoxy, phenylalkoxy, cyanoalkoxy, alkylsulphenyl, alkylsulphinyl, alkylsulphonyl, aminosulphonyl, alkylaminosulphonyl, dialkylaminosulphonyl, alkylsulphoximino, alkenyloxy or alkynyloxy group, R2 denotes a hydrogen atom, a hydroxyl, alkoxy, phenylalkoxy, amino, alkylamino or dialkylamino group, R3 denotes a hydrogen atom or an alkoxy group and R4 denotes a hydrogen or halogen atom, or a cyano, nitro, amino, carboxyl, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, aminocarbonylamino, alkylaminocarbonylamino or dialkylaminocarbonylamino group, their tautomers and their acid addition salts have useful pharmacological properties, in particular an effect on the blood pressure and on the contractility of the heart muscle. The novel compounds can be prepared by processes known for analogous compounds.
Bibliography:Application Number: DE19833346575