VERFAHREN ZUR HERSTELLUNG VON CYCLOPROPANCARBONSAEUREESTERN

• Main Authors: SZEKELY,ISTVAN,DR, GASPAR,MARIANNE,.. LOVASZ GEB, DUKAI,JOZSEF,..DR, SOOS,RUDOLF,..DR, KOVACS,GABOR,..DR
• Format: Patent
• Language: German
• Published: 15.01.1981
• Edition: 3
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; AGRICULTURE; ANIMAL HUSBANDRY; APPARATUS THEREFOR; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; FISHING; FORESTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HUNTING; METALLURGY; ORGANIC CHEMISTRY; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; TRAPPING

A process is disclosed for the preparation of an optically active or racemic cyclopropanecarboxylic acid of the formula (I) (I) wherein R1 and R2 are the same or different and each is lower alkyl or halogen; R is a member of a group which contains various cyclic structures as set forth in the specification, the DIFFERENCE valency bond represents alpha - and/or beta -configuration; the - valency bond represents beta -configuration, which comprises reacting an optically active or racemic cyclopropanecarboxylic acid of the formula (VII) (VII) with a dimethyl-methylidene-ammonium salt of the formula (VIII) (VIII) wherein X is halogen or lower alkoxy and Y- is a halide or lower alkylsulfate ion in an anhydrous, inert organic solvent, and sebsequently reacting a dimethyl-acloxy-methylidene-ammonium salt thus obtained with an optically active, inactive or racemic alcohol of the formula R-OH without isolation, in the presence of an organic base.