ANTIMIKROBIELLE MITTEL

• Main Authors: BUECHEL,DR.,KARL-HEINZ, PLEMPEL,MANFRED,DR, KRANZ,ECKART,DR, HALLER,INGO,DR
• Format: Patent
• Language: German
• Published: 30.07.1981
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

1. Antimycotic agent, characterised in that it contains at least one triazolyl-alkanediol derivative of the general formula see diagramm : EP0033088,P13,F2 in which R**1 represents tert.-butyl, sec-butyl, isopropyl, chloro-tert.-butyl, bromo-tert.-butyl, fluoro-tert.-butyl, 1,3-dichloro-2-methyl-prop-2-yl, 2-methylcarbamoyloxy-prop-2-yl, 2-diethylcarbamoyloxy-prop-2-yl, methysulphonyloxy-tert.-butyl, phenylsulphonyloxy-tert.-butyl, 4-chlorophenylsulphonyloxy-tert.-butyl, acetoxy-tert.-butyl, ethylcarbonyloxy-tert.-butyl, phenylcarbonyloxy-tert.-butyl, 4-chlorophenylcarbonyloxy-tert.-butyl, diethylaminosulphonyloxy-tert.-butyl, methoxy-tert.-butyl, ethoxy-tert.-butyl, isopropoxy-tert.-butyl, phenoxy-tert.-butyl, or 4-chlorophenoxy-tert.-butyl, or phenyl, chlorophenyl, dichlorophenyl, chloro-methyl-phenyl, bromophenyl, nitrophenyl, biphenylyl, nitrobiphenylyl, chlorobiphenylyl, phenoxyphenyl, chlorophenoxyphenyl, benzylphenyl or chlorobenzylphenyl, and R**2 represents trichloromethyl, dichlorofluoromethyl, trifluoromethyl, dichloromethyl, chloromethyl, 1,1,2-trichloroethyl, 1,1-dibromoethyl, 1,1-dichloroethyl, 1,1,2-trichloro-propyl, 2-chloro-prop-2-yl, 1,2,2-trichlorovinyl ; 2,2-dichlorovinyl, methoxycarbonyl or ethoxycarbonyl, and physiologically acceptable acid addition salts and metal salt complexes thereof.