NEUES VERFAHREN ZUR HERSTELLUNG VON N-CYCLOHEXYL-N-METHYL-N-(2-AMINO-3,5- DIBROMBENZYL)-AMIN
For the preparation of N-cyclohexyl-N-methyl-N-(2-amino-3,5-dibromobenzyl)amine, 3-bromo-2-nitrobenzyl bromide is used as a starting substance and is reacted with N-methylcyclohexylamine in the presence of an acid acceptor. The nitro group of the resultant N-cyclohexyl-N-methyl- 2-nitro-3-bromobenzy...
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Main Authors | , , , , |
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Format | Patent |
Language | German |
Published |
12.05.1977
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Edition | 2 |
Subjects | |
Online Access | Get full text |
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Summary: | For the preparation of N-cyclohexyl-N-methyl-N-(2-amino-3,5-dibromobenzyl)amine, 3-bromo-2-nitrobenzyl bromide is used as a starting substance and is reacted with N-methylcyclohexylamine in the presence of an acid acceptor. The nitro group of the resultant N-cyclohexyl-N-methyl- 2-nitro-3-bromobenzylamine is then reduced and the resulting N-cyclohexyl-N-methyl-2-amino-3-bromobenzylamine is brominated. This process enables the preparation of this compound in a simple manner with a yield of more than 80%. The compound has excellent bronchosecretolytic action and can be used in the therapy of chronic, non-specific disorders of the airways. |
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Bibliography: | Application Number: DE19762633518 |