Isolation of vincristine from vinca rosa l - in improved yields

Title cpd. (I) useful as an antileukemia agent is prepd. by oxidising vinblastine with chromic acid at a low temp. sepg. the mixt. including N-dimethyl vinblastine (II) formylating (II) and sepg. (I), esp. by chromatography.

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Bibliographic Details
Main Authors JOVANOVICS GEB. NAGY, KAROLINA, SZASZ, KALMAN, FEKETE, GYOERGY, BITTNER, EMIL, DEZSERI, ESZTER, ELES, JANOS
Format Patent
LanguageEnglish
German
Published 06.06.1974
Edition1
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Title cpd. (I) useful as an antileukemia agent is prepd. by oxidising vinblastine with chromic acid at a low temp. sepg. the mixt. including N-dimethyl vinblastine (II) formylating (II) and sepg. (I), esp. by chromatography.
Bibliography:Application Number: DE19722259388