Endothelin-Rezeptor-Antagonisten

• Main Authors: CHRISTADLER, MARIA, 63322 ROEDERMARK, DE, WILM, CLAUDIA., 64367 MUEHLTAL, DE, ANZALI, SOHEILA., 64297 DARMSTADT, DE, DORSCH, DIETER., 64372 OBER-RAMSTADT, DE, OSWALD, MATHIAS., 64673 ZWINGENBERG, DE, MEDERSKI, WERNER., 64390 ERZHAUSEN, DE, SCHMITGES, CLAUS., 64823 GROS-UMSTADT, DE
• Format: Patent
• Language: German
• Published: 28.08.1997
• Edition: 6
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The invention concerns compounds of formula (I), in which R is (i), (ii) or (iii); n is 0, 1 or 2; X means O or S; and R , R , R and R have different meanings, or a cyclized tautomeric shape. The invention also concerns the (E) isomers and salts of these compounds which display endothelin receptor a...