Endothelin-Rezeptor-Antagonisten

The invention concerns compounds of formula (I), in which R is (i), (ii) or (iii); n is 0, 1 or 2; X means O or S; and R , R , R and R have different meanings, or a cyclized tautomeric shape. The invention also concerns the (E) isomers and salts of these compounds which display endothelin receptor a...

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Main Authors CHRISTADLER, MARIA, 63322 ROEDERMARK, DE, WILM, CLAUDIA., 64367 MUEHLTAL, DE, ANZALI, SOHEILA., 64297 DARMSTADT, DE, DORSCH, DIETER., 64372 OBER-RAMSTADT, DE, OSWALD, MATHIAS., 64673 ZWINGENBERG, DE, MEDERSKI, WERNER., 64390 ERZHAUSEN, DE, SCHMITGES, CLAUS., 64823 GROS-UMSTADT, DE
Format Patent
LanguageGerman
Published 28.08.1997
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention concerns compounds of formula (I), in which R is (i), (ii) or (iii); n is 0, 1 or 2; X means O or S; and R , R , R and R have different meanings, or a cyclized tautomeric shape. The invention also concerns the (E) isomers and salts of these compounds which display endothelin receptor antagonistic properties.
Bibliography:Application Number: DE19961007096