Cpds. of formulae (I)-(III) where X="blocked" primary amino gp. e.g. phthalimido, tritylamino, o-nitrophenoxyacetamido, o-nitrophenylsulphenylamino, carbo

Cpds. of formulae (I)-(III) where X="blocked" primary amino gp. e.g. phthalimido, tritylamino, o-nitrophenoxyacetamido, o-nitrophenylsulphenylamino, carbobenzoxyamino, formylamino, carbo-t-butoxyamino Note: only cpd. (II) is claimed, together with its acid addn. salts. (I) and (III) as int...

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Bibliographic Details
Main Author CLARK SHEEHAN,JOHN
Format Patent
LanguageEnglish
German
Published 04.03.1971
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Cpds. of formulae (I)-(III) where X="blocked" primary amino gp. e.g. phthalimido, tritylamino, o-nitrophenoxyacetamido, o-nitrophenylsulphenylamino, carbobenzoxyamino, formylamino, carbo-t-butoxyamino Note: only cpd. (II) is claimed, together with its acid addn. salts. (I) and (III) as intermediates in the synthesis of penicillins and cephalosporins (procedures given). (II) as intermediate to mothproofing agents and pickling inhibitors. 3-Phthalimido-4-mercapto-2-azetidinone is reacted with N2H4.H2O (1 equiv.) in dioxan at room temp. for 12 hr. HCl is added to ppt. phthalhydrazide, which is filtered off and the filtrate lyophilised to provide (II).HCl.
Bibliography:Application Number: DE19691943160