DE1917057

(A) A water insoluble enzyme prepn. (I) (B) Improved method for 6-aminopenicillanic acid. Deacylation of penicillin. A suitable acylase, obtd. e.g. from E. coli or fungal sources, is reacted with a suitable reactive carboxymethylcellulose, Zeocarb 226 acid chloride, or hydrazine cross-linked ethylen...

Full description

Saved in:
Bibliographic Details
Main Authors POWELL, LAWSON WILLIAM, WORTHING, SUSSEX, GB, CARRINGTON, THOMAS RONALD, GORING-BY-SEA, SUSSEX, GB, SAVIDGE, THOMAS ADRIAN, STEYNING, SUSSEX, GB
Format Patent
LanguageEnglish
Published 08.09.1983
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HETEROCYCLIC COMPOUNDS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:(A) A water insoluble enzyme prepn. (I) (B) Improved method for 6-aminopenicillanic acid. Deacylation of penicillin. A suitable acylase, obtd. e.g. from E. coli or fungal sources, is reacted with a suitable reactive carboxymethylcellulose, Zeocarb 226 acid chloride, or hydrazine cross-linked ethylene-maleic anhydride resins, tog. with the appropriate amide-forming reagent, e.g. DCCD. The coupled enzyme is esp. useful of for deacylation of benzyl and phenoxymethylpenicillins to 6-aminopenicillanic acid of high purity.
Bibliography:Application Number: DE19691917057