Niedermolekulare Inhibitoren von Guaninnucleotid-Austauschfaktoren der Cytohesin-Familie

• Main Authors: HAFNER, MARKUS, TAPPERTZHOFEN, BARBARA, KOLANUS, WALDEMAR, THEIS, MIRKO, FAMULOK, MICHAEL, GRUENE, IMKE
• Format: Patent
• Language: German
• Published: 24.05.2006
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

Die vorliegende Erfindung betrifft Arzneimittel und deren Verwendung, wobei die Arzneimittel Verbindungen ausgewählt sind aus der Gruppe, umfassend die allgemeinen Formeln (1), (2), (3), (4) und/oder deren Enantiomere, Diastereomere sowie deren pharmazeutisch verträgliche Salze umfassen. Diese Arzneimittel sind geeignet zur Behandlung von Autoimmunerkrankungen, Tumorerkrankungen und/oder zur Immunsuppression. The invention relates to a pharmaceutical composition and the use thereof, wherein the pharmaceutical composition contains compounds selected from a group of general formulas (5), (6), (7) and (8) and/or enantiomers, diastereomers or the pharmaceutically acceptable salts thereof. The pharmaceutical composition is used for treating autoimmune and tumoral diseases and/or for immunosuppresion.