Avilamycin-Derivate

• Main Authors: MUEHLENWEG, AGNES, BECHTHOLD, ANDREAS, TREFZER, AXEL, WEITNAUER, GABRIELE
• Format: Patent
• Language: German
• Published: 12.09.2002
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS THEREOF; CULTURE MEDIA; DERIVATIVES THEREOF; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; ORGANIC MACROMOLECULAR COMPOUNDS; POLYSACCHARIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; SUGARS; THEIR PREPARATION OR CHEMICAL WORKING-UP; VINEGAR; WINE

The invention relates to avilamycin derivatives, genetic engineering, biosynthetic methods for the production thereof, medicaments containing said compounds and the utilization of said compounds for the production of a medicament against infectious diseases. The invention also relates to the nucleic acids, proteins and gene clusters and corresponding cells connected to the production of said avilamycin derivatives. Die Erfindung betrifft Avilamycin-Derivate, gentechnologische biosynthetische Verfahren zu deren Herstellung, Arzneimittel enthaltend diese Verbindungen, sowie die Verwendung dieser Verbindungen zur Herstellung eines Arzneimittels gegen Infektionskrankheiten wie auch Nucleinsäuren, Proteine und Gencluster und entsprechende Zellen, die mit der Herstellung dieser Avilamycin-Derivate verbunden sind.