VERFAHREN ZUM HERSTELLEN VON 2-AMINO-OXAZOLIN-VERBINDUNGEN
In the disclosed process, an O ,2 min anhydro-1-( beta -D-arabinofuranosyl)thymine is formed by condensing a 2-amino- beta -arabinofurano[1 min ,2 min :4,5,]-2-oxazoline with a compound of the formula wherein R1 is C1-C4 alkyl; X is halogen or OR2, wherein R2 is H, C1-C4 alkyl or phenyl; in the pres...
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Main Author | |
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Format | Patent |
Language | German |
Published |
18.07.1991
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Edition | 5 |
Subjects | |
Online Access | Get full text |
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Summary: | In the disclosed process, an O ,2 min anhydro-1-( beta -D-arabinofuranosyl)thymine is formed by condensing a 2-amino- beta -arabinofurano[1 min ,2 min :4,5,]-2-oxazoline with a compound of the formula wherein R1 is C1-C4 alkyl; X is halogen or OR2, wherein R2 is H, C1-C4 alkyl or phenyl; in the presence of a suitable solvent at about 0 DEG C to about 150 DEG C. Catalytic agents such as dimethylaminopyridine and triethylamine may also be added to accelerate the reaction. Protected intermediates of the anhydronucleosides and aminooxazolines are also disclosed. |
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Bibliography: | Application Number: DD19890337873 |