VERFAHREN ZUR GEWINNUNG VON N-GLYKOSIL-DERIVATEN DER POLYENMAKROLIDE SOWIE DEREN SALZE,VORZUGSWEISE N-METHYLGLUKAMIN-SALZE

The amino group-containing polyene macrolide is reacted with a mono- or oligosaccharide of the aldose or ketose series in an organic solvent or an organic solvent mixture. In order to be able to use an inexpensive, non-flammable solvent, the N-glycosyl derivative produced is precipitated from the re...

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Main Authors BOROWSKI,EDWARD,PL, DAHLIG,HALINA,PL, ROSLIK-KAMINSKA,DANUTA,PL, KOWSZYK-GINDIFER,ZUZANNA,PL, ZIELINSKI,JAN,PL, PAWLAK,JAN,PL, FALKOWSKI,LEONARD,PL, PLOCIENNIK,ZOFIA,PL, KOLODZIEJCZYK,PAWEL,PL, BYLEC,ELZBIETA,PL, JAKOBS,EWA,PL, GOLIK,JERZY,PL, WAGNER,WLADYSLAWA,PL
Format Patent
LanguageGerman
Published 11.01.1978
Edition2
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:The amino group-containing polyene macrolide is reacted with a mono- or oligosaccharide of the aldose or ketose series in an organic solvent or an organic solvent mixture. In order to be able to use an inexpensive, non-flammable solvent, the N-glycosyl derivative produced is precipitated from the reaction medium by means of water or an aqueous solution of an inorganic salt, purified by crystallisation from a higher alcohol, and optionally converted into a salt.
Bibliography:Application Number: DD19770198505