Crystalline anhydrous mofetil mycophenolate and intravenous formulation thereof

Krystalick², bezvod² mykofenol t mofetilu strukturn ho vzorce I, kter² je komplexov n jako s l s aniontem vybran²m ze skupiny sest vaj c z chloridu, s ranu, fosfore nanu a octanu, a zejm na hydrochloridov s l, intraven zn prost°edky a jejich soupravy.\ In the present invention there is disclosed a c...

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Bibliographic Details
Main Authors FLEITMAN JEFFREY S, ROZZOLIO MICHELE C, LEUNG DE MEI, FU ROGER CHERNG
Format Patent
LanguageCzech
English
Published 17.09.2003
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Krystalick², bezvod² mykofenol t mofetilu strukturn ho vzorce I, kter² je komplexov n jako s l s aniontem vybran²m ze skupiny sest vaj c z chloridu, s ranu, fosfore nanu a octanu, a zejm na hydrochloridov s l, intraven zn prost°edky a jejich soupravy.\ In the present invention there is disclosed a crystalline anhydrous mofetil mycophenolate of the structural formula I, wherein the compound is complexed as a salt with an anion selected from the group consisting of chloride, sulfate, phosphate and acetate, in particular the hydrochloride salt. The invention also relates to intravenous formulations as well as kits thereof.
Bibliography:Application Number: CZ19960000788