Heterocyclic substituted derivatives of phenyl-cyclohexanecarboxylic acid; process of their preparation, their use and pharmaceutical preparation in which these compounds are comprised

• Main Authors: KNORR ANDREAS DR, FEY PETER DR, HUBSCH WALTER DR, WOHLFEIL STEFAN DR, STASCH JOHANNES-PETER DR, DRESSEL JURGEN DR, HANKO RUDOLF H. DR, MULLER-GLIEMANN MATTHIAS DR, MULLER ULRICH E. DR, KAZDA STANISLAV DR, KRAMER THOMAS DR, BEUCK MARTIN DR, ZAISS SIEGFRIED DR
• Format: Patent
• Language: Czech; English
• Published: 14.11.2001
• Edition: 7
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

e en se t²k heterocyklicky substituovan²ch deriv t kyseliny fenyl-cyklohexankarboxylov obecn ho vzorce I, ve kter m maj substituenty specifick v²znamy, jako i jejich pou it v l ivech, obzvl t jako krevn tlak sni uj c ch a antiaterosklerotick²ch prost°edk . Uveden slou eniny se vyrob reakc odpov daj c ch heterocyklick²ch slou enin s cyklohexanbenzylhalogenidy.\ The present invention relates to heterocyclic substituted derivatives of the phenyl-cyclohexanecarboxylic acid of the general formula I, in which the individual substituents have specific meanings, as well as their use in medicament, particularly as blood pressure reducing agents and anti-atherosclerotic preparations. The indicated compounds are prepared by reacting corresponding heterocyclic compounds with cyclohexane benzyl halides.