CONVERSION PROCESS OF SULFHYDRYL GROUP TO DISULFIDE GROUP IN COMPOUNDS CONTAINING SULFHYDRIL GROUP
Thiols are trapped, and converted to disulfide compounds, by a process of reacting them with compounds containing a 1,2,4-thiadiazole ring structure carrying a substituent at position 3 of the thiadiazole ring, and being unsubstituted at position N-2. The process is useful pharmacologically, in inhi...
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Main Authors | , , , , , |
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Format | Patent |
Language | Czech English |
Published |
13.01.1999
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | Thiols are trapped, and converted to disulfide compounds, by a process of reacting them with compounds containing a 1,2,4-thiadiazole ring structure carrying a substituent at position 3 of the thiadiazole ring, and being unsubstituted at position N-2. The process is useful pharmacologically, in inhibiting certain thiol-containing enzymes such as H+/K+-ATPase (the proton pump), and industrially, in selective removal of thiol compounds from gas or liquid mixtures. |
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Bibliography: | Application Number: CZ19980002713 |