Composition containing chitosan-glucan intended for healing wounds and preventing adhesion of bandage to wound

• Main Authors: EULAKOVA ROMANA, VELEBNY VLADIMIR, VALENTOVA ZUZANA, BILEROVA HELENA
• Format: Patent
• Language: Czech; English
• Published: 15.04.2009
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Rešení se týká prípravku, obsahujícího farmakologicky vhodný chitosan-glukanový komplex nebo jeho sul, bud samostatne nebo v kombinaci s jedním nebo více polysacharidy nebo jejich vhodnými solemi a antiseptikum, který je urcený pro hojení ran a který je soucasne s urychlováním hojení schopen zabránit adhezi bandáže na ránu. Prípravek podle vynálezu po aplikaci neprímo podporuje hojivé procesy v ráne a odvádí prebytecný sekret spolu s tkánovými mediátory a enzymy, které hojení podporují. Tím zajistí ráne a jejímu okolí potrebnou hydrataci, aniž by docházelo k maceraci okolní kuže nebo prisychání k ráne. Prídavek antiseptických látek zabrání další infekci. Prípravek obsahuje 0,01-100 hmotn. % chitosan-glukanového komplexu, 0-99,99 hmotn. % jiného polysacharidu a 0-50 hmotn. % antiseptika. The invention relates to a preparation containing a pharmacologically suitable chitosan-glucan complex or a salt thereof, either alone or in combination with one or more polysaccharides or suitable salts thereof and an antiseptic agent, that is intended for wound healing and that, besides accelerating wound healing, is at the same time able to prevent a bandage adhesion to the wound. The preparation according to the invention, having been applied, indirectly supports the healing processes in the wound and drains the redundant secretion together with the tissue mediators and enzymes that support the healing. By doing this, it provides for the necessary hydration of the wound and its surroundings, without any maceration of the surrounding skin or drying and sticking to the wound. An addition of antiseptic agents prevents a further infection. The preparation contains 0.01 to 100% by weight of chitosan-glucan complex, 0 to 99.99% by weight of another polysaccharide and 0 to 50% by weight of an antiseptic agent.