Novel process for preparing N-(1,1-dimethylethyl)-4-[[5 -ethoxy-4-cis-[2-(4-morpholino)ethoxy]-2 -oxospiro[cyclohexan-1,3 -[3H]indol]-1 (2 H)-yl]sulfonyl]-3-methoxybenzamidw and a salt thereof

The invention relates to a process for the preparation of a compound of formula (I) and the salts thereof by reacting the compound of formula (II) with the compound of formula (III), which comprises carrying out the reaction in dimethyl sulfoxide, at a temperature between 10° C. and 40° C., preferab...

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Main Authors GONCZI CSABA, SIMON KALMAN, HAIASZ JUDIT, SZOMOR TIBORNE, CSIKOS EVA, EROSNE TAKACSY TUNDE, SANTANE CSUTOR ANDREA, SAROSI PETER, HERMECZ ISTVAN, HEJA GERGELY, NAGY LAJOS, SZVOBODA GYORGYNE, MAJLATH CSILLA
Format Patent
LanguageCzech
English
Published 13.11.2002
Edition7
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Summary:The invention relates to a process for the preparation of a compound of formula (I) and the salts thereof by reacting the compound of formula (II) with the compound of formula (III), which comprises carrying out the reaction in dimethyl sulfoxide, at a temperature between 10° C. and 40° C., preferably at room temperature and transforming the resulting base of formula (I), if desired, into its salt by a method known per se.
Bibliography:Application Number: CZ20020000145