CAPTOPRYL TABLETS

The invention relates to captopril tablets comprising a filler and binding agent, a disintegrating agent, a lubricant and a glidant agent wherein the filler and binding agent is a 1.5:1 - 1:1 weight ratio mixture of lactose and microcrystalline cellulose and the total amount of said mixture is 60-80...

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Bibliographic Details
Main Authors FEKETE PAL, KRISZTIAN MARIA, SZENTGROTI PALNE, PALFI ZOLTANNE, LADY BLANKA, GORA LASZLONE
Format Patent
LanguageCzech
English
Published 16.09.1998
Edition6
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Summary:The invention relates to captopril tablets comprising a filler and binding agent, a disintegrating agent, a lubricant and a glidant agent wherein the filler and binding agent is a 1.5:1 - 1:1 weight ratio mixture of lactose and microcrystalline cellulose and the total amount of said mixture is 60-80 % by weight of the totalweight of the tablet. The captopril tablets of the present invention are highly stable, can be readily manufactured and the standard deviation of the active ingredient content of the individual tablets and also of the parts of tablets split into two or four parts is very low.
Bibliography:Application Number: CZ19980001194