SUBSTITUTED MONOPYRIDYLMETHYLPYRIDONES AND BIPYRIDYLMETHYLPYRIDONES, PROCESS OF THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS IN WHICH THEY ARE COMPRISED

• Main Authors: KNORR ANDREAS DR, FEY PETER DR, HUBSCH WALTER DR, WOHLFEIL STEFAN DR, DRESSEL JURGEN DR, STASCH JOHANNES-PETER DR, HANKO RUDOLF DR, MULLER ULRICH DR, DENZER DIRK DR, MULLER-GLIEMANN MATTHIAS DR, KAZDA STANISLAV DR, BISCHOFF HILMAR DR, KRAMER THOMAS DR, BEUCK MARTIN DR, ZAISS SIEGFRIED DR
• Format: Patent
• Language: English
• Published: 16.11.1994
• Edition: 5
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Substituted mono- and bipyridylmethylpyridones are prepared either by reaction of pyridones with mono- or bipyridylmethylhalogen compounds or by reaction of pyridone-substituted halopyridines with tetrazolylphenylboronic acids. The substituted mono- and bipyridylmethylpyridones can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.