METHOD OF 5 (6)-THIOCYANATOBENZIMIDAZOLE'S DERIVATIVES PRODUCTION

The method of preparation of derivatives of 5(6)-thiocyanatobenzimidazole of general formula I, where R means alkoxycarbonyl amino group with 1 or 2 carbon atoms in alkoxyl part, consists in the fact that the compound of general formula II, in which R is of the above mentioned meaning, is let to rea...

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Main Authors PALOSI ENDRE ,HU, MARVANYOS EDE ,HU, KORBONITS DEZSO ,HU, SZVOBODA IDA ROZ. KANZEL,HU, HEJA GERGELY ,HU, KOVACS VERA ROZ. MINDLER,HU, SZOMOR MARIA ROZ. WUNDELE,HU, HORVATH KAROLY ,HU, NAGY LIVIA ROZ. KORANYI,HU, GONCZI CSABA ,HU, KISS PAL ,HU, KUN JUDIT ,HU
Format Patent
LanguageEnglish
Published 12.11.1991
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The method of preparation of derivatives of 5(6)-thiocyanatobenzimidazole of general formula I, where R means alkoxycarbonyl amino group with 1 or 2 carbon atoms in alkoxyl part, consists in the fact that the compound of general formula II, in which R is of the above mentioned meaning, is let to react with gas chlorine and rhodanide of general formula III, in which R is the atom of alkaline metal, metal of alkaline earths or amino group.The compounds prepared in the above-described manner are intermediate products in production of benzimidazole derivatives, known as anthelmintics.
Bibliography:Application Number: CS19850004822