DERIVADOS DE PIPERIDINONA COMO INHIBIDORES MDM2 PARA EL TRATAMIENTO DE CÁNCER

• Main Authors: WANG, XIAODONG, DUQUETTE, JASON, DEIGNAN, JEFFREY, FISHER, BENJAMIN, MCGEE, LAWRENCE, EKSTEROWICZ, JOHN, MCINTOSH, JOEL, ZHU, JIANG, BECK, HILARY PLAKE, FU, JIASHENG, GUSTIN, DARIN JAMES, LI, ZHIHONG, JOHNSON, MICHAEL, MCMINN, DUSTIN, LAI, SUJEN, REW, YOSUP, HUANG, XIN, SUN, DAQING, WANG, YINGCAI, HEATH, JULIE ANNE, MEDINA, JULIO CESAR, BARTBERGER, MICHAEL DAVID, GONZALEZ LOPEZ DE TURISO, FELIX, LIU, JIWEN, CONNORS, RICHARD VICTOR, KOPECKY, DAVID JOHN, MA, ZHIHUA, FU, ZICE, MIHALIC, JEFFREY THOMAS, YAN, XUELEI, FOX, BRIAN MATTHEW, LOW, JONATHAN DANTE, CHEN, XIAOQI, JIAO, XIANYUN, KAYSER, FRANK, GRIBBLE, JR., MICHAEL WILLIAM, OLSON, STEVEN HOWARD, ROVETO, PHILIP MARLEY, GONZALEZ BUENROSTRO, ANA, LUCAS, BRIAN STUART, YU, MING, LI, YIHONG
• Format: Patent
• Language: Spanish
• Published: 11.03.2013
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

La presente invención proporciona compuestos de inhibidor MDM2 de la Fórmula I. The present invention provides MDM2 inhibitor compounds of Formula IE,which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.