COMPUESTOS DE AMINOHETETOARILO O SUSTITUIDOS CON PIRAZOL COMO INHIBIDORES DE PROTEINA QUINASA

Se proporcionan compuestos de fórmula I Compounds of formula 1 are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.

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Bibliographic Details
Main Authors NAMBU, MITCHELL, DAVID, JIA, LEI, FUNK, LEE, ANDREW, KUNG, PEI-PEI, CUI, JINGRONG, JEAN, PAIRISH, MASON, ALAN, TRAN-DUBE, MICHELLE BICH, MENG, JERRY, JIALUN, SHEN, HONG
Format Patent
LanguageSpanish
Published 14.09.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Se proporcionan compuestos de fórmula I Compounds of formula 1 are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.
Bibliography:Application Number: CR20120000421