DERIVADOS DE (TIO)MORFOLINA COMO MODULADORES DE S1P

La presente invención se refiere a derivados de (tio)morfolina que tienen la fórmula (I) The present disclosure relates to (thio)morpholine derivatives of the formula (I) or a pharmaceutically acceptable salt, a solvate or hydrate thereof; with the proviso that the derivative of formula (I) is not 2...

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Main Authors IWEMA BAKKER, WOUTER, I, COOLEN, HEIN K.A.C, MONS, HARMEN, KAM, VAN DER, ELIZABETH, FRANKENA, JURGEN, RONKEN, ERIC, STOIT, AXEL
Format Patent
LanguageSpanish
Published 28.05.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:La presente invención se refiere a derivados de (tio)morfolina que tienen la fórmula (I) The present disclosure relates to (thio)morpholine derivatives of the formula (I) or a pharmaceutically acceptable salt, a solvate or hydrate thereof; with the proviso that the derivative of formula (I) is not 2-(4-ethylphenyl)-4-morpholinoethanol or 4-[4-(2-hydroxyethyl)-2-morpholinyl]benzeneacetonitrile or a pharmaceutically acceptable salt, a solvate or hydrate thereof. The compounds of the invention have affinity to S1P receptors and may be used in the treatment, alleviation or prevention of S1P receptor mediated diseases and conditions.
Bibliography:Application Number: CR20120000153