Formulaciones del esteroide c21-n-pirazolilo 19-nor c3,3-disustituido y métodos de uso de este

• Main Authors: STUTZMAN, Todd Anthony, NARAYAN, Padma, WILKERSON, Carolyn, MENG, Jianing, CHEN, Xiaoxia, BERNER, Bret, JAIN, Raj Ramnik, WATSON, Paul Steven
• Format: Patent
• Language: Spanish
• Published: 07.03.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Esta invención se refiere a un esteroide C21-pirazolilo 19-nor C3,3-disustituido de fórmula (I) y composiciones farmacéuticas de este. También se divulgan en el presente documento métodos para preparar las composiciones farmacéuticas del esteroide C21-pirazolilo 19-nor C3,3-disustituido de fórmula (I) y métodos de uso del esteroide C21-pirazolilo 19-nor C3,3-disustituido de fórmula (I) o formas sólidas cristalinas, sales farmacéuticamente aceptables y composiciones farmacéuticamente aceptables de este. This invention relates to a 19-nor C3,3-disubstituted C21-pyrazolyl steroid of formula (I) and pharmaceutical compositions thereof. Also disclosed herein are methods of making the pharmaceutical compositions of the 19-nor C3,3-disubstituted C21-pyrazolyl steroid of formula (I) and methods of using the 19-nor C3,3-disubstituted C21-pyrazolyl steroid of formula (I) or crystalline solid forms, pharmaceutically acceptable salts, and pharmaceutically acceptable compositions thereof.