THIAZOLIDINECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME

The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl o...

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Bibliographic Details
Main Authors ZOLTAN GYORGYDEAK, REZSO BOGNAR GEZA HORVUTH, ISTVAN KOVACS
Format Patent
LanguageEnglish
Published 22.04.1987
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin.
Bibliography:Application Number: CN19861004085