PROCESS FOR THE PREPARATION OF ISOTHIURONIUM SALTS COMPOUNDS

Isothiuronium salts of the general formula (I), (wherein, R is C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, aralkyl or aryl, the said groups being optionally substituted by one or more hydroxy, mercapto and/or halogen; R stands for hydrogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl or C3-6...

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Bibliographic Details
Main Authors LAJOS GUCZOGHY, ATTILA MOLNAR, CSABA VERTESI
Format Patent
LanguageEnglish
Published 17.09.1986
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Isothiuronium salts of the general formula (I), (wherein, R is C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, aralkyl or aryl, the said groups being optionally substituted by one or more hydroxy, mercapto and/or halogen; R stands for hydrogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl or C3-6 cycloalkyl; X represents an organic or inorganic anion). The compounds and salts of the present invention can be prepared by reacting a compound of the general formula (II), with an agent capable of introducing a R group. The compounds of the general formula (I) exhibit antitumor and immunostimulant effect and are useful in therapy.
Bibliography:Application Number: CN19851003160