Special integrated spray needle column for glycopeptide and glycoprotein

• Main Authors: DAI MIAN, ZHANG QUANQING, ZHU CHENXIN
• Format: Patent
• Language: Chinese; English
• Published: 10.12.2021
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The utility model discloses a special integrated spray needle column for glycopeptide and glycoprotein, which comprises an integrated spray needle column shell and a special filler, the integrated spray needle column shell has a hollow structure and comprises a column body and a spray needle for electrospray; the whole hollow structure of the integrated spray needle column shell is filled with the special filler, and the special filler is special filler for separating silicon-based glycopeptide and glycoprotein. By adopting the integrated spray needle column disclosed by the utility model, on-line separation and electrospray ionization can be realized during high performance liquid chromatography separation for glycopeptides and glycoproteins in complex samples, separation and mass spectrum electrospray integration can be realized, time can be saved, the loss of samples is less, the dead volume behind the separation column is small, the separation degree is high, and the identification efficiency is high. 本实用