Rifamycin analogs and uses thereof
The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other...
Saved in:
Main Author | |
---|---|
Format | Patent |
Language | English |
Published |
10.01.2007
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3'-hydroxy analogs, 4'- and/or 6' halo and/or alkoxy analogs, and various 5' substituents that incorporate a cyclic amine moiety. |
---|---|
Bibliography: | Application Number: CN200480031078 |