Piperidine compound and method for producing same

Disclosed are a novel piperidine compound represented by the general formula [I] below which has an excellent tachykinin receptor antagonizing activity and pharmacologically acceptable salts thereof. [I] In the formula, ring A represents an optionally substituted benzene ring; ring B represents an o...

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Bibliographic Details
Main Author TAKAHASHI MASAMI,MIYAKE TSUTOMU,YAMANAKA TAKESHI,ASAI HIDETOSHI,KONO RIKAKO
Format Patent
LanguageEnglish
Published 27.12.2006
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are a novel piperidine compound represented by the general formula [I] below which has an excellent tachykinin receptor antagonizing activity and pharmacologically acceptable salts thereof. [I] In the formula, ring A represents an optionally substituted benzene ring; ring B represents an optionally substituted benzene ring; R represents an optionally substituted hydroxyl group, a thiol group having a substituent, a sulfonyl group having a substituent, or a group represented by the following formula [II]: wherein R represents a carbonyl group having a substituent or a sulfonyl group having a substituent and R represents a hydrogen atom or an optionally substituted alkyl group; R represents a hydrogen atom or the like; Z represents an oxygen atom or a group represented by -N(R )- wherein R represents an optionally substituted alkyl group or the like; R represents an optionally substituted alkyl group; and R represents an optionally substituted alkyl group.
Bibliography:Application Number: CN200480034978