8-chloro-2,3-benzodiazepine derivatives

The invention relates to new 8-chloro-2,3-benzodiazepine derivatives of the general formula (I),wherein R stands for a lower alkyl group or a group of the general formula -NH-R', wherein R' stands for a lower alkyl or a lower cycloalkyl group), and pharmaceutically acceptable acid addition...

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Bibliographic Details
Main Author BARKOCZY JOZSEF,LING ISTVAN,SIMIG GYULA,SZENASI GABOR,GIGLER GABOR,KERTESZ SZABOLCS,SZUECS GYULA,SZABO GEZA,VEGH MIKLOS,HARSING LASZLO GABOR
Format Patent
LanguageEnglish
Published 29.11.2006
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention relates to new 8-chloro-2,3-benzodiazepine derivatives of the general formula (I),wherein R stands for a lower alkyl group or a group of the general formula -NH-R', wherein R' stands for a lower alkyl or a lower cycloalkyl group), and pharmaceutically acceptable acid addition salts thereof. The invention also encompasses a process for the preparation of said compounds, pharmaceutical compositions containing them and new intermediates useful for the preparation of the new 8-chloro-2,3-benzodiazepine derivatives.The compounds according to the invention possess AMPA/kainate receptor inhibiting activity.
Bibliography:Application Number: CN200480025409