Use of dapsone as a neuroprotector in cerebral infarction

The invention relates to the use of dapsone as the first effective treatment against the disabling consequences associated with cerebral infarction in patients. Dapsone was evaluated as a neuroprotector in the cerebral infarction model produced by the occlusion of the middle cerebral artery in rats...

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Bibliographic Details
Main Author RIOS CASTANEDA LUIS C. PERIFER,ALTAGRACIA MARTINEZ M. CAL DEL,NADER KAWACHI J. PUENTE DE PIED,KRAVZOV JINICH J
Format Patent
LanguageEnglish
Published 25.10.2006
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to the use of dapsone as the first effective treatment against the disabling consequences associated with cerebral infarction in patients. Dapsone was evaluated as a neuroprotector in the cerebral infarction model produced by the occlusion of the middle cerebral artery in rats and in patients suffering from acute cerebral infarction caused by thromboembolism. In both studies, dapsone displayed a reduction of between 70 and 90 % in the adverse effects which occur as a consequence of the infarction.
Bibliography:Application Number: CN200480026445