Method for producing solid galenic formulations using a crosslinked non-thermoplastic carrier
Production of a solid dosage form (A) involves: (1) forming a shapable mass comprising (by weight) 50-99.4% crosslinked, non-thermoplastic carrier (I), 0.5-30 wt. % adjuvant(s) (II) selected from thermoplastic polymers, lipids, sugar alcohols (or derivatives) and solubilizers and 0.1-49.5% active ag...
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Main Author | |
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Format | Patent |
Language | English |
Published |
30.11.2005
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | Production of a solid dosage form (A) involves: (1) forming a shapable mass comprising (by weight) 50-99.4% crosslinked, non-thermoplastic carrier (I), 0.5-30 wt. % adjuvant(s) (II) selected from thermoplastic polymers, lipids, sugar alcohols (or derivatives) and solubilizers and 0.1-49.5% active agent(s) (III) at or above the softening point of (II) (but at 70 degrees C or more); and (2) cooling. |
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Bibliography: | Application Number: CN200380100979 |