Method for preparing effective anti-virus cyclopropane derivative and intermediate used thereof

In one aspect, the invention provides a cyclopropane derivative represented by formula (I) : wherein B represents a purine derivative residue. In other aspects the invention provides (3-oxa-2-oxobicyclo[3.1.0]hexan-1-yl)methanol and a method of preparing a cyclopropane derivative of formula (I) from...

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Bibliographic Details
Main Authors MATSUZAWA TOSHIHIRO, TSUJI NAOSHI, ONISHI TOMOYUKI
Format Patent
LanguageEnglish
Published 27.08.2003
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:In one aspect, the invention provides a cyclopropane derivative represented by formula (I) : wherein B represents a purine derivative residue. In other aspects the invention provides (3-oxa-2-oxobicyclo[3.1.0]hexan-1-yl)methanol and a method of preparing a cyclopropane derivative of formula (I) from this compound comprising replacement of the hydroxyl group of the compound with a leaving group followed by reaction with a purine derivative.
Bibliography:Application Number: CN20021006971