Antibiotics composition with synergistic effect to generation of beta lactamase medicine-resisting strain

The antibiotic composition is a compound preparation made up by using third generation cephalosporin antibiotics cefatriaxone sodium and beta-lactamasa inhibitor sulbactam according to the anhydrous weight ratio of 1:1-8:1. Said composition not only can protect the cefatriazone sodium and prevent be...

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Bibliographic Details
Main Authors XIANGCAI LI, YUGUO ZHONG, GUOXU YIN
Format Patent
LanguageEnglish
Published 26.03.2003
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The antibiotic composition is a compound preparation made up by using third generation cephalosporin antibiotics cefatriaxone sodium and beta-lactamasa inhibitor sulbactam according to the anhydrous weight ratio of 1:1-8:1. Said composition not only can protect the cefatriazone sodium and prevent beta-lactamasa produced by drug-resistant bacteria from damaging it, but also can raise its antibiotic activity, and can be used for clinical application, and can produce obvious synergistic effect for curing drug-resistant strain infection. Said invented composition can be made into compound preparation and suitable for industrial production.
Bibliography:Application Number: CN2002133976