Method for preparing lysophosphatidylethanolamine

Disclosed herein is a method for purifying the lysophosphatidylethanolamine with high purity by treating the phospholipid mixture with enzymes, followed by solvent fractionaltion without the column purification. The method of the present invention comprises hydrolyzing phospholipid mixture containin...

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Bibliographic Details
Main Authors YANG YOUNG-LAE, CHUNG GUK-HOON
Format Patent
LanguageEnglish
Published 12.03.2003
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
SPIRITS
VINEGAR
WINE
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Summary:Disclosed herein is a method for purifying the lysophosphatidylethanolamine with high purity by treating the phospholipid mixture with enzymes, followed by solvent fractionaltion without the column purification. The method of the present invention comprises hydrolyzing phospholipid mixture containing 10-99 weight % of phosphatidylethanolamine with phospholipase A2 to produce lysophospholipid; and treating the lysophospholipid with the solvent mixture comprising water and one or more organic solvents selected from the group consisting of low alcohol, hydrocarbon and alkylester to eliminate impurities except lysophosphatidylethanolamine.
Bibliography:Application Number: CN20008016445