Substituted phenylacetamides and their use as glucokinase activators

2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a polar ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of type II diabetes.

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Bibliographic Details
Main Author CORBETT WENDY LEA,GRIMSBY JOSEPH SAMUEL,HAYNES NANCY-ELLEN,KESTER ROBERT FRANCIS,MAHANEY PAIGE ERIN,RACHA JAGDISH KUMAR,SARABU RAMAKANTH,WANG KA
Format Patent
LanguageEnglish
Published 01.08.2007
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a polar ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of type II diabetes.
Bibliography:Application Number: CN20038009383