Compositions containing benzoxazinone and nucleoside like materials

Certain benzoxazinones of the formula: wherein: X is halo, X is trihalomethy, or pentahaloethyl; Z is O; are useful in the inhibition of HIV reverse transcriptase (including its resistant varieties), the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, phar...

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Bibliographic Details
Main Author S. D. YOUNG,L. S. PAYNE,W. C. LUMA JR
Format Patent
LanguageEnglish
Published 30.05.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Certain benzoxazinones of the formula: wherein: X is halo, X is trihalomethy, or pentahaloethyl; Z is O; are useful in the inhibition of HIV reverse transcriptase (including its resistant varieties), the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
Bibliography:Application Number: CN19991018108