Anti-HIV fusogenic peptide and its production method

Anti-HIV fusogenic peptide and its production are disclosed. Formula is a-WX1EWDX2X3LX4X5YTSX6LX7X8LIX9X10SX11X12QQX13KNEX14ELX15X16-b, a is one of ethanoyl, 9-fluorenylmethoxy-carboxide and tert-butoxy-carboxide; and b is amino or carboxyl. The polypeptide liquid-phase synthesis is carried out by c...

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Bibliographic Details
Main Author SHANHE,WEN WAN
Format Patent
LanguageEnglish
Published 23.05.2007
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:Anti-HIV fusogenic peptide and its production are disclosed. Formula is a-WX1EWDX2X3LX4X5YTSX6LX7X8LIX9X10SX11X12QQX13KNEX14ELX15X16-b, a is one of ethanoyl, 9-fluorenylmethoxy-carboxide and tert-butoxy-carboxide; and b is amino or carboxyl. The polypeptide liquid-phase synthesis is carried out by coupling intermediate peptide under activating agent and removing protecting group. Its advantages include low cost, high activity, less by-effect and simple synthesis.
Bibliography:Application Number: CN200510034136