4-(phenyl-piperazinyl-methyl)benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestional disorders

Compounds of general formula I R 1 is selected from any one of phenyl, furanyl, and pyrrolyl, wherein each of phenyl, pyrrolyl, and furanyl may optionally and independently be substituted by 1 or 2 substituents selected from CF 3 , methyl, chloro, fluoro, bromo, and iodo; R 2 is independently select...

Full description

Saved in:
Bibliographic Details
Main Author W. BROWN,C. WALPOLE,N. PLOBECK
Format Patent
LanguageEnglish
Published 16.08.2006
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:Compounds of general formula I R 1 is selected from any one of phenyl, furanyl, and pyrrolyl, wherein each of phenyl, pyrrolyl, and furanyl may optionally and independently be substituted by 1 or 2 substituents selected from CF 3 , methyl, chloro, fluoro, bromo, and iodo; R 2 is independently selected from ethyl and isopropyl; R 3 is independently selected from hydrogen and fluoro; and R 4 is -NH 2 ; or salts thereof or separate enantiomers and salts thereof; are disclosed and claimed in the present application, as well as separate enantiomers of the compounds and salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain, anxiety and functional gastrointestinal disorders.
Bibliography:Application Number: CN20028014169