Method of synthetizing alpha-aryl propionic acid by carbonyl process

An oxonation process for synthesizing alpha-arylpropanoic acid includes under the existance of carried Pd catalyst hydrogenating arylethanone to generate alpha-arylalcohol and oxonating reaction under the existance of phosphonic ligand, acidic medium and CO by in-situ catalysis to generate alpha-ary...

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Bibliographic Details
Main Authors YUAN KOU, BAOHAN XIE, CHUNGU XIA
Format Patent
LanguageEnglish
Published 07.07.1999
Edition6
Subjects
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Summary:An oxonation process for synthesizing alpha-arylpropanoic acid includes under the existance of carried Pd catalyst hydrogenating arylethanone to generate alpha-arylalcohol and oxonating reaction under the existance of phosphonic ligand, acidic medium and CO by in-situ catalysis to generate alpha-arylpropanoic acid. Its advantages are no need of separating and regenerating catalyst so hydrogenating and oxonating reactions can take place in same container and high chemical output rate up to 94%.
Bibliography:Application Number: CN1997125639