Substances and methods for treating macular degeneration

• Main Authors: DICK ANDREW, LIU JIAN, CHANG YINGKAI
• Format: Patent
• Language: Chinese; English
• Published: 23.08.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The present invention relates to a substance that increases IRAK-M expression and/or IRAK-M activity for use in a method of treating or preventing macular degeneration in a subject. The substance may be one or more of a small molecule, a nucleic acid, a vector virion, a polypeptide, a nucleic acid system, a viral vector system, or a pharmaceutical composition. 本发明涉及提高IRAK-M表达和/或IRAK-M活性的物质，其用于在对象中治疗或预防黄斑变性的方法中。所述物质可以是小分子、核酸、载体病毒体、多肽、核酸系统、病毒载体系统或药物组合物中的一种或更多种。